ISSN 2149-2247 | E-ISSN 2149-2549
Case Report
Co-existence of Goldenhar and Klinefelter Syndromes in a Patient Born Following ICSI
1 Private Clinic, Denizli, Turkey  
2 Adana Numune Training and Research Hospital, Adana, Turkey  
3 Department of Medical Genetics, Pamukkale University Faculty of Medicine, Denizli, Turkey  
4 Department of Gynecology and Obstetrics, Pamukkale University Faculty of Medicine, Denizli, Turkey  
5 Private Clinic, İzmir, Turkey  
Erciyes Med J 2018; 40: 164-165
DOI: 10.5152/etd.2018.0098
Key Words: Goldenhar syndrome, Klinefelter syndrome, intracytoplasmic sperm injection
Abstract

Intracytoplasmic sperm injection (ICSI) is a widespread and powerful method enabling men with low sperm quantity and quality to become fathers. However, compared with naturally conceived children, there are increased risks of problems, such as congenital malformations, chromosomal abnormalities, infertility, epigenetic diseases, and delayed neuropsychological development in the offspring. We present the case of 6-year-old male patient born following ICSI with clinical and radiological features of Goldenhar syndrome as well as a history of surgery for unilateral cryptorchidism. His karyotyping showed a chromosomal constitution of 47, XXY. Clinicians should be aware of the risks of an increasing number of patients born following ICSI to maximize children’s health and welfare.


Cite this article as
: Zeybek S, Sarıkepe B, Bağcı G, Alataş E, Düzcan F. Co-existence of Goldenhar and Klinefelter Syndromes in a Patient Born Following ICSI. Erciyes Med J 2018; 40(3): 164-5.

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