ISSN: 2149-2247 | E-ISSN: 2149-2549

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Is There a Relationship Between Microvascular Complications and the Severity of Type 2 Diabetes Mellitus? [Erciyes Med J]
Erciyes Med J. 2020; 42(1): 71-77 | DOI: 10.14744/etd.2019.33230

Is There a Relationship Between Microvascular Complications and the Severity of Type 2 Diabetes Mellitus?

Funda Çatan1, Abdülbari Bener2, Mustafa Öztürk3
1Department of Biostatistics and Medical Informatics, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Turkey; Department of Computer Education and Instructional Technologies, Kastamonu University Faculty of Education, Kastamonu, Turkey
2Department of Biostatistics and Medical Informatics, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Turkey; Department of Evidence for Population Health Unit, School of Epidemiology and Health Sciences, University of Manchester, Manchester, UK; Regenerative and Restorative Medicine Research Centre, İstanbul Medipol University International School of Medicine, İstanbul, Turkey
3Regenerative and Restorative Medicine Research Centre, İstanbul Medipol University International School of Medicine, İstanbul, Turkey; Department of Endocrinology and Metabolism, İstanbul Medipol University International School of Medicine, İstanbul, Turkey

Objective: The aim of this study was to determine the relationship between microvascular Type 2 diabetes mellitus (T2DM) complications and the severity and duration of diabetes in the light of sociodemographic and lifestyle variables.
Materials and Methods: This is a prospective cohort study based on 899 (527 females, 372 males) patients with T2DM aged 25–70 years. Patient information including socio-demographic variables; body mass index (BMI); lifestyle habits and duration of diabetes; treatment of diabetes; values for hemoglobin A1c (HbA1c); development of diabetes complications; and the presence of neuropathy, nephropathy, and retinopathy were recorded. A univariate and multivariate statistical analysis were performed.
Results: Significant differences were found between diabetics with HbA1c ≤7 and >7 in terms of the education level, occupation, household income, duration of diabetes, the number of children, smoking, physical exercise, eating fast food, control regularity, and diabetes education. A total of 17.1% of patients had diabetic retinopathy, 17.0% had neuropathy, and 13.7% had nephropathy. Among diabetics, 2.3% had three microvascular complications, whereas 66.6% had none of them. The prevalence of diabetes complications was lower in patients who had good glycemic control than those who had poor glycemic control. Furthermore, the highest reduction in the level of HbA1c was for sulfonylurea usage.
Conclusion: A high prevalence of diabetes complications is a burden for both the patients and the health care system. Screening, early diagnosis, management of the glucose level, and the follow-up may result in delayed diabetes complications.

Keywords: Diabetes, severity of type 2 diabetes, microvascular complications.

Funda Çatan, Abdülbari Bener, Mustafa Öztürk. Is There a Relationship Between Microvascular Complications and the Severity of Type 2 Diabetes Mellitus?. Erciyes Med J. 2020; 42(1): 71-77

Corresponding Author: Funda Çatan, Türkiye
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