ISSN: 2149-2247 | E-ISSN: 2149-2549
Fever of Unknown Origin (FUO): Towards a Uniform Definition and Classification System [Erciyes Med J]
Erciyes Med J. 2020; 42(2): 121-126 | DOI: 10.14744/etd.2020.56667

Fever of Unknown Origin (FUO): Towards a Uniform Definition and Classification System

Mile Bosilkovski1, Magdalena Baymakova2, Marija Dimzova1
1University Hospital for Infectious Diseases and Febrile Conditions, Medical Faculty, “Ss Cyril and Methodius” University, Skopje, Republic of Macedonia
2Department of Infectious Diseases, Military Medical Academy, Sofia, Bulgaria

Despite the great advancements seen in medicine in recent years, fever of unknown origin (FUO) remains a serious diagnostic challenge. Regardless of the etiological elucidation in many cases of FUO and the progress seen in the management of these patients, there are currently many weaknesses in this area as a result of inconsistency in the definition and interpretation of key terminology and the utilization of different definitions and classifications. As a result, there is confusion among medical practitioners about FUO, which leads to laborious and difficult comparisons among different case series. This study outlines the mismatch in terminology and diversity found in the classification of the conditions that cause FUO and emphasizes the discrepancies between what some terminology intends to represent and what it actually represents in reality. Thus, we attempted to determine an appropriate solution for established inconsistencies.

Keywords: Diagnostic approach, fever, fever of unknown origin, infection, neoplasm.

Mile Bosilkovski, Magdalena Baymakova, Marija Dimzova. Fever of Unknown Origin (FUO): Towards a Uniform Definition and Classification System. Erciyes Med J. 2020; 42(2): 121-126

Corresponding Author: Mile Bosilkovski, Republic of Northern Macedonia
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