ISSN: 2149-2247 | E-ISSN: 2149-2549
Therapeutic Plasma Exchange in G6PD Deficient Patient Complicated with Intravascular Hemolysis: A Case Report [Erciyes Med J]
Erciyes Med J. 2020; 42(2): 223-225 | DOI: 10.14744/etd.2019.63239

Therapeutic Plasma Exchange in G6PD Deficient Patient Complicated with Intravascular Hemolysis: A Case Report

Esra Ermis Turak1, Rehab Helmy Mohamed Ibrahim2, Fahir Öztürk1, Koray Demir1, Mehmet Fatih Karamustafaoğlu1, Volkan Kahraman1, Çiğdem Pala3, Leylagül Kaynar4, Mustafa Çeti&775;n4, Dr. Elias Fadel1
1Bahrain Oncology Center, King Hamad University Hospital, Kingdom of Bahrain
2Department of Hematopathology, King Hamad University Hospital, Kingdom of Bahrain
3Department of Hematology, University of Health Sciences, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey
4Department of Hematology, Erciyes University Faculty of Medicine, Kayseri, Turkey

Glucose-6-phosphate dehydrogenase is an enzyme that protects the erythrocytes against oxidative damage. G6PD deficiency is a common disorder in Gulf Countries that may present with hemolytic anemia and acute renal failure after exposure to oxidative triggers, such as drug, infection or some foodstuffs. In this study, a severe and complicated case of a G6PD deficient patient was presented. A 65-year old G6PD deficient patient presented with acute renal failure and intravascular hemolysis after eating fava beans. Therapeutic plasma exchange was used in the patient for two consecutive days. Clinical and laboratory findings were improved with plasma exchange. Although supportive therapy is enough for mild cases, therapeutic plasma exchange can be life-saving in complicated cases.

Keywords: Plasma exchange, free hemoglobin, G6PD, kidney injury, hemolysis

Esra Ermis Turak, Rehab Helmy Mohamed Ibrahim, Fahir Öztürk, Koray Demir, Mehmet Fatih Karamustafaoğlu, Volkan Kahraman, Çiğdem Pala, Leylagül Kaynar, Mustafa Çeti&775;n, Dr. Elias Fadel. Therapeutic Plasma Exchange in G6PD Deficient Patient Complicated with Intravascular Hemolysis: A Case Report. Erciyes Med J. 2020; 42(2): 223-225

Corresponding Author: Esra Ermis Turak, Bahrain
LookUs & Online Makale