ISSN: 2149-2247 | E-ISSN: 2149-2549

Quick Search




Diffusion-Weighted Magnetic Resonance Imaging Value in the Detection and Differentiation of Bone Tumors and Tumor-Like Lesions [Erciyes Med J]
Erciyes Med J. 2019; 41(2): 141-147 | DOI: 10.14744/etd.2019.68878

Diffusion-Weighted Magnetic Resonance Imaging Value in the Detection and Differentiation of Bone Tumors and Tumor-Like Lesions

Mostafa Emara1, Ayman Nada1, Maged Hawana2, Mohamed Elazab1, Ahmed Mohamed Shokry1
1Department of Diagnostic and Interventional Radiology, National Cancer Institute, Cairo University, Cairo, Egypt
2Department of Diagnostic and Interventional Radiology, Cairo University Kasr Al Ainy Faculty of Medicine, Cairo, Egypt

Objective: The aim of this study was to evaluate the ability of diffusion-weighted magnetic resonance imaging (MRI) and its corresponding apparent diffusion coefficient (ADC) values in the detection, characterization, and discrimination between different types of bony lesions.
Materials and Methods: Patients were evaluated by conventional and diffusion-weighted MR images. Diffusion was carried out using the b values of 0, 500, and 1000, and then the ADCs were generated.
Results: The average ADC value of benign lesions was approximately 1.84×10–3 mm2/s±0.33, while that of malignant lesions was approximately 1.17×10–3 mm2/s±0.44; p<0.001. The receiver operating characteristic (ROC) curve analysis produced a cut-off value for the detection of malignancy of 1.47×10–3 mm2/s with 89.5% specificity and 79.5% sensitivity.
Conclusion: Diffusion-weighted imaging combined with ADC values is considered a useful tool that can be added to the conventional MRI sequences for detection, differentiation, and characterization of different bony lesions.

Keywords: Magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC), bone tumors, benign, malignant, tumor like

Mostafa Emara, Ayman Nada, Maged Hawana, Mohamed Elazab, Ahmed Mohamed Shokry. Diffusion-Weighted Magnetic Resonance Imaging Value in the Detection and Differentiation of Bone Tumors and Tumor-Like Lesions. Erciyes Med J. 2019; 41(2): 141-147

Corresponding Author: Ayman Nada, Egypt
LookUs & Online Makale