ISSN: 2149-2247 | E-ISSN: 2149-2549
Erciyes Medical Journal Vitamin D Level and the Association with Morbidity and Mortality in Critically Ill Patients: A Single-center Study [Erciyes Med J]
Erciyes Med J. 2020; 42(4): 411-416 | DOI: 10.14744/etd.2020.40771

Vitamin D Level and the Association with Morbidity and Mortality in Critically Ill Patients: A Single-center Study

Gülseren Elay1, Kürşat Gündoğan2, İsmail hakkı Akbudak3, Zuhal Özer Şimşek2, Şahin Temel2, Muhammet Güven2, Murat Sungur2
1Department of Intensive Care, Erciyes University Faculty of Medicine, Kayseri, Turkey; Department of Intensive Care, Gaziantep University Faculty of Medicine, Gaziantep, Turkey
2Department of Intensive Care, Erciyes University Faculty of Medicine, Kayseri, Turkey
3Department of Intensive Care, Erciyes University Faculty of Medicine, Kayseri, Turkey; Department Intensive Care, Pamukkale University Faculty of Medicine, Denizli, Turkey

Objective: The present study aims to evaluate vitamin D (Vit D) level in critically ill patients and to assess its level about morbidity and mortality.
Materials and Methods: This study was conducted in an intensive care unit (ICU). Vit D level was measured on admission, third and seventh day.
Results: Of the 62 patients, the median Vit D level at baseline and on the third and seventh days was 12.8 mcg/L, 8.35 mcg/L, and 9.30 mcg/L, respectively. Vitamin D level was low (<30 mcg/L) in 92% of patients at baseline and 97% on the third day. 23% of the studied patients developed a new site infection. No statistically difference in the Vit D level at baseline, or on the third or seventh day based on the presence of infection (p=0.556, p=0.404, p=0.439, respectively). The most commonly seen infections were ventilator-associated pneumonia (VAP) and catheter-related bloodstream infection (CRBSI). The growth of Acinetobacter baumannii was the most frequent. Vit D level (p>0.05) might not have a causal role in mortality (ICU, 30-day, and 6-month), and no correlation was found between them.
Conclusion: The level of Vit D was low. Our study did not show any relationship between mortality rates and Vit D level, but VAP and CRBSI were observed.

Keywords: Acinetobacter baumannii, critical illness, intensive care unit, mortality, new site infection, vitamin D.

Gülseren Elay, Kürşat Gündoğan, İsmail hakkı Akbudak, Zuhal Özer Şimşek, Şahin Temel, Muhammet Güven, Murat Sungur. Vitamin D Level and the Association with Morbidity and Mortality in Critically Ill Patients: A Single-center Study. Erciyes Med J. 2020; 42(4): 411-416

Corresponding Author: Kürşat Gündoğan, Türkiye
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